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Related Concept Videos

Trachea01:22

Trachea

The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of the...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Obstructive Pulmonary Disease II: Emphysema01:23

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.
The Bronchial Tree01:23

The Bronchial Tree

The human bronchi and bronchial tree play a crucial role in the respiratory system, facilitating the exchange of oxygen and carbon dioxide. Let's delve into the intricate structure and functions of these respiratory components.
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...

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Related Experiment Video

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Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation
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Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation

Published on: November 10, 2023

Obstructive inflammatory tracheal pseudomembrane.

Astrid Crespo-Lessmann1, Alfons Torrego-Fernández

  • 1Servicio de Neumología, Hospital de la Santa Creu i Sant Pau, Barcelona, España. acrespo@santpau.cat

Archivos De Bronconeumologia
|February 20, 2013
PubMed
Summary

This case report details an obstructive inflammatory tracheal pseudomembrane, a rare complication of repeated intubation. Conservative treatment successfully resolved this tracheal septum, highlighting a less invasive management option.

Keywords:
BronchoscopyBroncoscopiaIntubaciónIntubationPseudomembrana traquealTracheal pseudomembrane

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Last Updated: May 14, 2026

Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation
06:15

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Published on: November 10, 2023

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Transuterine Fetal Tracheal Occlusion Model in Mice

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Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
09:10

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

Published on: January 20, 2010

Area of Science:

  • Pulmonology
  • Critical Care Medicine
  • Otolaryngology

Background:

  • Artificial airways, such as endotracheal tubes, can lead to acquired tracheal pathologies including stenosis, granulomas, and pseudomembranes.
  • Circumferential tracheal stenosis is the most common presentation in adults, often necessitating endoscopic intervention.
  • Tracheal pseudomembranes, particularly inflammatory types, can cause significant airway obstruction and respiratory complications.

Observation:

  • A case of an obstructive inflammatory tracheal pseudomembrane presenting as a tracheal septum, secondary to repeated intubations, is described.
  • Clinical presentation typically involves respiratory infection and/or atelectasis post-extubation due to secretion accumulation.
  • The pseudomembrane obstructed the airway, mimicking a tracheal septum.

Findings:

  • Conservative management, including glucocorticoids, led to the spontaneous resolution of the inflammatory tracheal pseudomembrane.
  • The tracheal septum formation was successfully treated without the need for invasive endotracheal procedures.
  • This case demonstrates that conservative treatment can be effective for certain inflammatory pseudomembranes.

Implications:

  • Highlights the potential for conservative management of inflammatory tracheal pseudomembranes, reducing the need for invasive procedures.
  • Suggests that early recognition of pseudomembrane formation can guide treatment towards less invasive options.
  • Contributes to understanding the spectrum of artificial airway complications and their management strategies.