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Updated: May 14, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Incidence of infectious complications associated with central venous catheters in pediatric population
Viviane Rosado1, Paulo Augusto Moreira Camargos, Wanessa Trindade Clemente
1Infection Control Committee of Clinics Hospital, Federal University of Minas, Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.
Insights
Central venous catheters (CVC) are vital in pediatric intensive care. Removing CVCs within seven days significantly reduces the risk of catheter-associated infections (CAI), a key finding for improving patient safety.
Area of Science:
- Pediatric critical care medicine
- Infectious disease epidemiology
Background:
- Central venous catheters (CVCs) are indispensable in pediatric intensive care units (PICUs).
- Implementing preventive strategies during CVC insertion and maintenance is crucial for mitigating infection risks.
Purpose of the Study:
- To investigate the incidence of catheter-associated infections (CAI) in a Brazilian university hospital's PICU.
- To identify risk factors and preventive measures associated with CAI in pediatric patients.
Main Methods:
- A prospective cohort study was conducted over two years in a Brazilian university hospital's PICU.
- Data on 255 CVC insertions were collected, focusing on daily practices and patient outcomes.
- Patients were monitored throughout their hospital stay to track the occurrence of CAI.
Main Results:
- The incidence density of CAI was 13.55 per 1,000 CVC-days.
- No significant association was found between CAI risk and surgical hand antisepsis, maximum barrier precautions, or chlorhexidine skin antisepsis.
- Catheter use for less than 7 days demonstrated a protective effect against CAI (OR, 0.29; P < .01).
Conclusions:
- Healthcare teams should judiciously assess the necessity of CVCs and prioritize removal within seven days whenever feasible.
- Close clinical monitoring and careful consideration of additional blood cultures are recommended for patients with ongoing CVC indications.
Background:
Central venous catheters (CVC) are essential in intensive pediatric care units (PICU). Preventive measures during insertion and maintenance reduce infection risks.
Methods:
A prospective cohort study was conducted from January 2010 to December 2011 in a Brazilian university hospital PICU. Patients were followed throughout hospital stay to verify the occurrence of catheter-associated infection (CAI). An active search was performed of the daily prospective data related to the practice of CVC insertion.
Results:
There was a total of 255 catheter insertions with a CAI incidence density of 13.55/1,000 CVC-days. No association was found between an increased risk for infection and surgical hand antisepsis, the use of maximum barrier precautions, or the use of chlorhexidine for skin antisepsis, which were recommended for the prevention of CAIs. A multivariate analysis showed that catheter use for less than 7 days was protective (P < .01; odds ratio, 0.29; 95% confidence interval: 0.12-0.72).
Conclusion:
Health care teams responsible for CVC insertion should rigorously assess the need for CVC and remove them within 7 days when possible. For patients who have no indication for CVC removal, monitoring with clinical evaluation and requests for additional blood cultures should be scrutinized rigorously.
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