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Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
Published on: June 23, 2019
N-(5-Amino-1H-1,2,4-triazol-3-yl)pyridine-2-carboxamide
Javier Hernández-Gil1, Sacramento Ferrer, Rafael Ballesteros
1Departament de Química Inorgànica, Universitat de València, Vicent Andrés Estellés s/n, 46100 Burjassot, València, Spain.
Abstract:
The title compound, C(8)H(8)N(6)O, was obtained by the reaction of 3,5-diamino-1,2,4-triazole with ethyl 2-picolinate in a glass oven. The dihedral angles formed between the plane of the amide group and the pyridine and triazole rings are 11.8 (3) and 5.8 (3)°, respectively. In the crystal, an extensive system of classical N-H⋯N and N-H⋯O hydrogen bonds generate an infinite three-dimensional network.
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