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Related Experiment Video

Updated: May 14, 2026

A Method to Preserve Wetland Roots and Rhizospheres for Elemental Imaging
06:29

A Method to Preserve Wetland Roots and Rhizospheres for Elemental Imaging

Published on: February 15, 2021

Trust in nature.

Shu-Nong Bai1

  • 1State Key Laboratory of Protein and Plant Gene Research; College of Life Sciences; Peking University; Beijing, China.

Plant Signaling & Behavior
|February 22, 2013
PubMed
Summary
This summary is machine-generated.

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Histone deacetylase HDA18 regulates Arabidopsis root epidermal cell patterning by mediating positional information. Its mutation mimics chemical inhibition, suggesting a key role in cell fate determination.

Area of Science:

  • Plant Biology
  • Developmental Biology
  • Epigenetics

Background:

  • Arabidopsis root epidermis cell differentiation into hair (H) and non-hair (N) cells is position-dependent.
  • Positional information is sensed at the plasma membrane but its nuclear relay mechanism remains unclear.
  • Histone acetylation's role in mediating this positional information was previously proposed.

Discussion:

  • The histone deacetylase (HDAC) inhibitor Trichostatin A (TSA) induces N-to-H cell fate conversion.
  • Mutation of HDA18, a histone deacetylase, phenocopies TSA treatment, supporting HDA18's involvement.
  • This suggests HDA18 is crucial for relaying positional signals to the nucleus.

Key Insights:

  • HDA18 is a key regulator of cellular patterning in the Arabidopsis root epidermis.
Keywords:
ArabidopsisHDA18hitone deacetylationkinasesroot epidermis

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Last Updated: May 14, 2026

A Method to Preserve Wetland Roots and Rhizospheres for Elemental Imaging
06:29

A Method to Preserve Wetland Roots and Rhizospheres for Elemental Imaging

Published on: February 15, 2021

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Measuring Biophysical and Psychological Stress Levels Following Visitation to Three Locations with Differing Levels of Nature

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  • Histone deacetylation by HDA18 is involved in the epigenetic control of cell fate.
  • The study characterizes HDA18's function in mediating positional information for cell differentiation.
  • Outlook:

    • Further biochemical characterization of HDA18 is needed.
    • Investigating the precise molecular mechanisms by which HDA18 influences gene expression in root epidermal patterning.
    • Understanding HDA18's role could reveal novel epigenetic pathways in plant development.