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Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
X-ray Imaging01:24

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with X-rays, and by 1900, X-ray was widely...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...

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Related Experiment Video

Updated: May 14, 2026

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue
07:48

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue

Published on: September 30, 2022

Monochromatic computed tomography with a compact laser-driven X-ray source.

K Achterhold1, M Bech, S Schleede

  • 1Department of Physics and Institut for Medical Engineering, Technische Universität München, 85748 Garching, Germany.

Scientific Reports
|February 22, 2013
PubMed
Summary
This summary is machine-generated.

Laser-driven X-ray sources offer superior computed tomography (CT) image quality for quantitative analysis. These compact sources enable precise measurements of mass absorption coefficients, crucial for applications like osteoporosis risk assessment.

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Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution
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Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution

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Last Updated: May 14, 2026

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue
07:48

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Published on: September 30, 2022

Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution
08:41

Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution

Published on: August 16, 2012

Area of Science:

  • Medical Imaging
  • X-ray Physics
  • Materials Science

Background:

  • Laser-driven electron-storage rings generate tunable, monochromatic keV X-rays via inverse Compton scattering.
  • Monochromatic X-rays mitigate beam hardening, a significant issue in quantitative absorption coefficient determination.
  • Accurate absorption coefficients are vital for medical diagnostics, such as osteoporosis risk assessment.

Purpose of the Study:

  • To evaluate the quantitative computed tomography (CT) performance of a laser-driven compact electron-storage ring X-ray source.
  • To compare the CT image quality and quantitative accuracy of this novel source against a conventional rotating anode X-ray tube.

Main Methods:

  • Quantitative CT measurements were performed on a phantom sample using the laser-driven electron-storage ring X-ray source.
  • Mass absorption coefficients were determined experimentally.
  • Results were compared with those obtained using a rotating anode X-ray tube generator at various peak voltages.

Main Results:

  • The laser-driven electron-storage ring source yielded significantly higher CT image quality compared to the rotating anode source.
  • Quantitative measurements of mass absorption coefficients demonstrated superior accuracy with the novel X-ray source.
  • The monochromatic nature of the laser-driven source effectively eliminated beam hardening artifacts.

Conclusions:

  • Laser-driven electron-storage ring X-ray sources are highly promising for advanced preclinical radiography and tomography.
  • These sources provide enhanced CT image quality, especially for quantitative applications requiring precise absorption coefficient determination.
  • The compact size and cost-effectiveness further support their potential clinical utility.