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Imaging of Extracellular Vesicles by Atomic Force Microscopy
Published on: September 11, 2019
Superhydrophobic surfaces allow probing of exosome self organization using X-ray scattering
Angelo Accardo1, Luca Tirinato, Davide Altamura
1Istituto Italiano di Tecnologia-IIT, Nanostructures Department, Via Morego 30, 16163 Genova, Italy.
Nanoscale
|February 22, 2013
Abstract:
Drops of exosome dispersions from healthy epithelial colon cell line and colorectal cancer cells were dried on a superhydrophobic PMMA substrate. The residues were studied by small- and wide-angle X-ray scattering using both a synchrotron radiation micrometric beam and a high-flux table-top X-ray source. Structural differences between healthy and cancerous cells were detected in the lamellar lattices of the exosome macro-aggregates.

