Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The Alabama preterm birth prevention project.

R L Goldenberg1, R O Davis, R L Copper

  • 1Department of Obstetrics and Gynecology, University of Alabama, Birmingham.

Obstetrics and Gynecology
|June 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pathogens identified in the internal tissues and placentas of stillbirths: results from the prospective, observational PURPOSe study.

BJOG : an international journal of obstetrics and gynaecology·2023
Same author

Purpura, Occurring in Nervous Diseases.

Buffalo medical and surgical journal·2023
Same author

Preterm neonatal survival: what is the role of prognostic models?

BJOG : an international journal of obstetrics and gynaecology·2021
Same author

Antibiotics at delivery: do the benefits outweigh the risks?

BJOG : an international journal of obstetrics and gynaecology·2021
Same author

Maternal serum fructosamine levels and stillbirth: a case-control study of the Stillbirth Collaborative Research Network.

BJOG : an international journal of obstetrics and gynaecology·2021
Same author

Preventable stillbirths in India and Pakistan: a prospective, observational study.

BJOG : an international journal of obstetrics and gynaecology·2021

A preterm birth prevention program did not reduce adverse outcomes in high-risk women. Despite increased interventions, the program showed no significant benefits and led to more infant complications like intracranial hemorrhages.

Area of Science:

  • Obstetrics and Gynecology
  • Neonatal Medicine
  • Public Health

Background:

  • Preterm birth remains a significant challenge in maternal and infant health.
  • Effective prevention strategies are crucial, especially in high-risk, underserved populations.

Purpose of the Study:

  • To evaluate the effectiveness of a comprehensive preterm birth prevention program.
  • To assess the program's impact on birth weight, gestational age, and neonatal outcomes in a high-risk population.

Main Methods:

  • A randomized controlled trial involving 1000 high-risk women.
  • Intervention group received risk scoring, intensive weekly observation with cervical exams, and preterm labor education.
  • Control group received standard care.

Related Experiment Videos

Main Results:

  • No significant differences in mean birth weight, gestational age, or rates of spontaneous preterm delivery or low birth weight.
  • Higher rates of diagnosed preterm labor in the treatment group.
  • Increased intracranial hemorrhages and ventilator days in infants from the treatment group, though not statistically significant for mortality or respiratory distress syndrome.

Conclusions:

  • The tested preterm birth prevention program was not effective in this predominantly black, indigent population.
  • The program did not improve key neonatal outcomes and was associated with increased infant morbidity.