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Preventable stillbirths in India and Pakistan: a prospective, observational study
R L Goldenberg1, S Saleem2, S S Goudar3
1Columbia University, New York, NY, USA.
Summary
Most stillbirths in low-income countries are preventable. Key factors include managing maternal hypertension, antepartum hemorrhage, and small for gestational age infants, highlighting the need for improved obstetric care.
Area of Science:
- Obstetrics and Gynecology
- Perinatal Medicine
- Public Health
Background:
- Stillbirth rates are significantly higher in low-income settings compared to high-income settings.
- A substantial proportion of these stillbirths are potentially preventable with adequate medical care.
Purpose of the Study:
- To develop and apply a methodology for determining the proportion of potentially preventable stillbirths in low-income settings.
- To identify the primary conditions associated with preventable stillbirths in India and Pakistan.
Main Methods:
- A prospective observational study was conducted in maternity hospitals in India and Pakistan.
- 872 stillbirths (≥20 weeks gestation) were analyzed using comprehensive clinical, pathological, and laboratory data.
- Criteria were established to define potentially preventable stillbirths based on gestational age and clinical conditions.
Main Results:
- Over half (55.5%) of all analyzed stillbirths were deemed potentially preventable.
- For stillbirths at ≥28 weeks gestation and ≥1000g birthweight, 73.5% were considered potentially preventable.
- Common contributing factors included small for gestational age (SGA), maternal hypertension, and antepartum hemorrhage.
Conclusions:
- The majority of stillbirths in the study sites are preventable.
- Improved management of maternal hypertension, SGA, and antepartum hemorrhage is crucial for reducing stillbirth rates.
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