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Updated: May 14, 2026

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

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Update on retinal detachment surgery.

Stephen G Schwartz¹, Harry W Flynn, William F Mieler

¹Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17 Street, Miami, FL 33136, USA.

Current Opinion in Ophthalmology

|February 23, 2013

Summary

Rhegmatogenous retinal detachment is a significant cause of vision loss. While pars plana vitrectomy is effective, ongoing research explores new surgical tools and potential links between fluoroquinolones and retinal detachment.

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Area of Science:

Ophthalmology
Retinal Surgery

Background:

Rhegmatogenous retinal detachment (RD) is a critical cause of visual impairment.
Surgical management aims for anatomic and visual success.

Purpose of the Study:

To review current controversies and recent advancements in the surgical management of rhegmatogenous retinal detachment.

Main Methods:

Review of recent literature on retinal detachment development and surgical treatments.
Analysis of emerging surgical techniques and potential risk factors.

Main Results:

Pars plana vitrectomy (PPV) remains a highly effective primary surgical treatment for RD, particularly in pseudophakic individuals.
Delayed surgery for macula-on RD may not be detrimental and could offer benefits.

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Last Updated: May 14, 2026

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Published on: March 7, 2025

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

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Published on: September 11, 2013

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

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A potential association between oral fluoroquinolone use and RD onset is noted but requires further investigation.

Novel surgical materials, such as bioerodible scleral buckling agents and artificial vitreous substitutes, are under development.

Conclusions:

Retinal detachment continues to be a major contributor to vision loss.
Current surgical interventions achieve high success rates, but advancements are anticipated to further improve patient outcomes.