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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

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Related Experiment Videos

Evaluation of trabectome in open-angle glaucoma.

Masahiro Maeda1, Mitsunori Watanabe, Kazuo Ichikawa

  • 1Department of Ophthalmology, Gifu Red Cross Hospital, Gifu, Japan. mmaeda.eye@gmail.com

Journal of Glaucoma
|February 23, 2013
PubMed
Summary

Trabectome surgery effectively reduced intraocular pressure (IOP) by approximately 30% in Japanese glaucoma patients within six months. This glaucoma treatment is a safe alternative to traditional surgeries, with minimal vision-threatening complications observed.

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Area of Science:

  • Ophthalmology
  • Glaucoma Surgery
  • Minimally Invasive Glaucoma Surgery (MIGS)

Background:

  • Glaucoma is a leading cause of irreversible blindness worldwide.
  • Trabecular meshwork ablation is a surgical approach to reduce intraocular pressure (IOP).
  • The Trabectome device offers a minimally invasive option for glaucoma management.

Purpose of the Study:

  • To evaluate the efficacy and safety of the Trabectome device in Japanese glaucoma patients.
  • To assess the impact of Trabectome surgery on intraocular pressure (IOP) and medication usage.
  • To document intraoperative and postoperative outcomes, including adverse events.

Main Methods:

  • Trabectome surgery was performed on 80 eyes of 69 adult Japanese glaucoma patients.
  • Patients had varying degrees of glaucoma and prior surgical or laser treatments.
  • Intraocular pressure (IOP), medication use, corneal endothelial cell density, and visual acuity were measured pre- and post-operatively.

Main Results:

  • Mean preoperative IOP of 26.6 mmHg decreased to 17.4 mmHg at 6 months (28.7% reduction).
  • Adjunctive medication use decreased from 4.0 to 2.3 at 6 months.
  • No vision-threatening complications occurred; 16.3% required reintervention, and no significant endothelial cell loss was noted.

Conclusions:

  • Trabectome surgery is an effective and safe alternative for managing glaucoma in Japanese patients.
  • The procedure is associated with a significant IOP reduction of approximately 30% at 6 months.
  • Trabectome offers a promising option for glaucoma management with a favorable safety profile.