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Novel adipokines and bone metabolism
Yuan Liu1, Cheng-Yuan Song, Shan-Shan Wu
1Institute of Metabolism and Endocrinology, Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, China ; Geriatric Department, Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, China.
International Journal of Endocrinology
|February 23, 2013
Summary
Novel adipokines secreted by adipose tissue play a crucial role in bone metabolism. Understanding these adipokines offers new therapeutic targets for preventing and treating osteoporosis.
Area of Science:
- Endocrinology
- Bone Biology
- Metabolic Research
Background:
- Osteoporosis poses a significant societal burden due to high morbidity and fractures.
- Adipose tissue, the largest endocrine organ, influences bone through secreted adipokines.
- Adipocytes share a common lineage with osteoblasts, impacting bone remodeling.
Purpose of the Study:
- To highlight the complex relationship between bone metabolism and novel adipokines.
- To explore potential new targets for osteoporosis prediction and treatment.
Main Methods:
- Review of recent research on novel adipokines.
- Analysis of adipokine functions in bone remodeling.
Main Results:
- Several novel adipokines have been identified and extensively studied.
- These adipokines exhibit diverse functions affecting bone metabolism.
Conclusions:
- The intricate connection between novel adipokines and bone metabolism is critical.
- Targeting novel adipokines may offer promising strategies for osteoporosis management.
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