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Updated: May 13, 2026

Multi-layer Cortical Ca2+ Imaging in Freely Moving Mice with Prism Probes and Miniaturized Fluorescence Microscopy
Published on: June 13, 2017
[Network activity of frontal and motor cortex in situations of simple and difficult decision-making in cats]
Abstract:
The organization of frontal and motor cortex network activity in situations with simple (without a choice) and difficult decision-making when there is a possibility of behavior choice strategy is shown. At development of delay reflexes with one reinforcement (without a choice) animals did not differ on behavior and showed high criterion of right answers. The strategy of behavior of the same animals in the complicated situation, with "right" choice food reinforcement, was different and animals showed different abilities of problem solution. Distinctions in neuron ensembles organization of frontal and motor cortex in situations with simple and difficult decision-making was revealed. In difficult decision-making situation, the number of exciting interneuron interactions in motor cortex was decreased that assumed the organization of inhibition chains. In the same situation, frontal network activity was not changed, and the tendency to increase of these parameters was observed only in erroneous reactions.
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