[Herpes simplex].
Hannamari Välimaa1, Mikko Seppänen, Veijo Hukkanen
1Helsingin yliopisto, virologian osasto ja HUS, suu- ja leukasairauksien klinikka ja HUSLAB.
Duodecim; Laaketieteellinen Aikakauskirja
|February 26, 2013
Summary
Primary herpes simplex virus (HSV) infections in children are declining, with HSV-1 increasingly causing genital herpes. Antiviral treatments are effective for primary infections, reactivations, and neonatal cases, with new preventive strategies showing promise.
Area of Science:
- Virology
- Infectious Diseases
- Dermatology
Context:
- Herpes simplex virus (HSV) infections represent a significant public health concern.
- Shifting epidemiology shows a decrease in childhood primary infections but a rise in genital herpes cases attributed to HSV-1.
- Asymptomatic viral shedding and brief, symptomless recurrences complicate transmission dynamics.
Purpose:
- To provide an overview of the current landscape of herpes simplex virus infections.
- To discuss contemporary treatment strategies and recent advancements in antiviral therapies.
- To highlight the evolving patterns of HSV epidemiology, particularly the rise of HSV-1 in genital herpes.
Summary:
- Primary herpes simplex virus infections in early childhood are less common.
- Herpes simplex virus type 1 (HSV-1) is now a notable cause of genital herpes.
- Antiviral medications are crucial for managing primary infections and reactivations, with advancements in neonatal and prophylactic treatments.
Impact:
- Improved understanding of HSV epidemiology aids in targeted prevention and control efforts.
- Effective antiviral treatments offer better management for neonatal herpes and prevention of recurrent infections.
- Recognizing HSV-1 as a cause of genital herpes necessitates updated public health messaging and diagnostic approaches.
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