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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

The Rat Genome Database 2013--data, tools and users.

Stanley J F Laulederkind¹, G Thomas Hayman, Shur-Jen Wang

¹Human and Molecular Genetics Center, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226-3548, USA. slaulederkind@mcw.edu

Briefings in Bioinformatics

|February 26, 2013

Summary

This summary is machine-generated.

The Rat Genome Database (RGD) provides comprehensive genomic, genetic, and disease data for researchers worldwide. It supports translational research and benefits a broad scientific community, including bioinformaticians and tool developers.

Keywords:

database disease genome human rat

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Area of Science:

Genomics
Bioinformatics
Translational Research

Background:

The Rat Genome Database (RGD) was established over a decade ago.
It serves as a crucial genomic resource for researchers studying rats.

Purpose of the Study:

To provide a centralized, curated repository of rat genetic, genomic, pathway, and phenotype data.
To support translational research through comparative genomics and disease-focused information.

Main Methods:

Data integration of genetic, genomic, pathway, and phenotype information.
Development of disease-specific portals, GBrowse, and VCMap tools.
Curating and structuring data from molecular to organismal levels.

Main Results:

RGD offers access to structured, curated data for a global user base.
Comparative genomics data facilitates translational research across species (rat, mouse, human).
Data integration into other databases expands RGD's reach and impact.

Conclusions:

RGD is a valuable and growing resource for diverse scientific disciplines.
Its comprehensive data and tools enhance research in genetics, genomics, and disease.
The database's influence extends to bioinformaticians, tool developers, and curators, fostering broader scientific advancement.