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Rapid and sensitive LC-MS approach to quantify non-radioactive transition metal impurities in metal radionuclides

Dexing Zeng1, Carolyn J Anderson

  • 1Department of Radiology, University of Pittsburgh, 100 Technology Drive, Suite 452F, Pittsburgh, PA 15219, USA.

Chemical Communications (Cambridge, England)
|February 26, 2013
PubMed

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The role of the detectors in High-Performance Liquid Chromatography (HPLC) is to analyze the solutes as they exit from the chromatographic column. The detector recognizes the solute's property and generates corresponding electrical signals, which are converted into a readable graph of the detector's response versus elution time called a chromatogram at the computer. There are several types of HPLC detectors, each with its own advantages and limitations, depending on the analyte properties and...