[Brain glycolipids in experimental brain edema]

Quantitative and qualitative composition of gangliosides, sulfatides and cerebrosides were studied in normal state and in experimental brain edema by means of thin-layer chromatography. In the experimental edema content of mono- and disialogangliosides was decreased while tri- and tetrasialogangliosides were unaltered. Statistically distinct increase in content of sulfocerebrosides (sulfatide 1.2) was also detected in brain edema as compared with controls. At the same time, amount of cerebroside 2 was decreased, whereas increase in cerebroside I concentration was detected.