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Childhood granulomatous periorificial dermatitis with a good response to oral metronidazole
Clara Rodriguez-Caruncho1, Isabel Bielsa, M Teresa Fernandez-Figueras
1Dermatology Department, Hospital Universitari Germans Trias i Pujol, Universistat Autónoma de Barcelona, Barcelona, Spain.
Insights
Childhood granulomatous periorificial dermatitis (CGPD) is a facial rash in children. Oral metronidazole effectively treated a 9-year-old girl with CGPD, clearing her skin lesions.
Area of Science:
- Dermatology
- Pediatrics
Background:
- Childhood granulomatous periorificial dermatitis (CGPD) is a facial rash in children, part of the rosacea and perioral dermatitis spectrum.
- CGPD presents as papular eruptions around the mouth, nose, and eyes with a histopathologic granulomatous pattern.
Observation:
- A case study involving a 9-year-old girl diagnosed with CGPD.
Findings:
- The patient was treated with oral metronidazole, an antibiotic known for its efficacy in adult rosacea and safety profile in pediatric patients.
- Successful resolution of the papular eruptions was observed following metronidazole therapy.
Implications:
- Oral metronidazole represents a viable and effective treatment option for childhood granulomatous periorificial dermatitis.
- This finding supports the use of metronidazole in pediatric dermatology for specific granulomatous facial conditions.
Abstract:
Childhood granulomatous periorificial dermatitis (CGPD) is a condition included in the spectrum of rosacea and perioral dermatitis that affects prepubescent children. It is characterized by papular eruptions located around the mouth, nose, and eyes that histopathologically show a granulomatous pattern. We report a 9-year-old girl with CGPD who required treatment with an oral antibiotic. Oral metronidazole was administered because of its known efficacy in adult rosacea and its safety in children. The patient responded well to this therapy, showing resolution of the lesions.
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