Related Experiment Video
Updated: May 13, 2026

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
Published on: December 13, 2017
Thalamic deep brain stimulation for orthostatic tremor
Toby C Yaltho1, William G Ondo
1Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas, United States of America.
Background:
Orthostatic tremor is an uncommon disorder manifest by high frequency, low amplitude leg tremor upon weight bearing. Treatment with oral tremor agents is inconsistent and usually not satisfactory.
Methods:
We implanted bilateral ventralis intermedius nuclei deep brain stimulators into an 82-year-old male with refractory orthostatic tremor.
Results:
The patient had a marked subjective and objective improvement in leg and arm tremor, mainly manifested by an improved ability to stand.
Discussion:
Bilateral thalamic deep brain stimulation may be considered in refractory cases of orthostatic tremor.

