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Risk factors and outcomes of unplanned PICU postoperative admissions: a nested case-control study
Paulo Sergio Lucas da Silva1, Vânia Euzébio de Aguiar, Marcelo Cunio Machado Fonseca
1Pediatric Intensive Care Unit, Department of Pediatrics, Hospital Estadual de Diadema-UNIFESP, São Paulo, Brazil. psls.nat@terra.com.br
Insights
Unplanned intensive care admission (UIA) in children is linked to airway issues, anesthesia, and intraoperative hypoxia. Preventable adverse events in 25% of UIA cases highlight opportunities for quality improvement in pediatric care.
Area of Science:
- Pediatric Critical Care Medicine
- Anesthesiology
- Healthcare Quality Improvement
Background:
- Unplanned postoperative admission to Pediatric Intensive Care Units (PICUs), or unplanned intensive care admission (UIA), is infrequent but associated with increased morbidity and mortality.
- Limited data exists on the specific risk factors and outcomes for pediatric UIA.
Purpose of the Study:
- To investigate the prevalence of UIA in postoperative pediatric patients.
- To identify risk factors associated with UIA.
- To compare outcomes between UIA and non-UIA patients.
Main Methods:
- A case-control study was conducted at a tertiary university-affiliated hospital.
- 116 postoperative pediatric patients were monitored, with 28 identified as UIA cases and 88 as controls.
- Logistic regression analysis was used to determine predictors of UIA.
Main Results:
- The overall prevalence of UIA was 2.6%.
- Key predictors for UIA included airway abnormality (OR 16.2), anesthetic factors (OR 5.8), and intraoperative hypoxia (OR 7.4).
- UIA patients required longer mechanical ventilation (4.5 vs. 2 days), with 25% of UIA cases attributed to preventable adverse events.
Conclusions:
- Airway abnormalities, anesthetic factors, and intraoperative hypoxia are significant risk factors for pediatric UIA.
- Preventable adverse events are a substantial contributor to UIA, indicating potential for quality improvement initiatives.
- While UIA impacts ventilation duration, overall PICU and hospital length of stay did not differ significantly between groups.
Background:
Although unplanned postoperative admission to PICUs (unplanned intensive care admission [UIA]) is uncommon, it might be associated with increased costs, morbidity, and mortality. However, detailed knowledge of risk factors and outcomes after UIA in children is still lacking.
Objectives:
To determine prevalence, risk factors, and outcomes of UIA patients compared with non-UIA patients.
Design:
Case-control study.
Setting:
A tertiary university-affiliated hospital.
Patients:
All postoperative children admitted to the PICU were monitored for UIA. About 28 cases and 88 controls were included.
Interventions:
none.
Measurements And Main Results:
The overall prevalence of UIA was 2.6%. About 28 patients (24.1%) of 116 had unplanned admission. Multiple logistic regression revealed that factors predicting UIA were airway abnormality (odds ratio 16.2, 95% confidence interval 2.65-99.6), anesthetic factors (odds ratio 5.8, 95% confidence interval 1.06-32.2), and hypoxia intraoperative (odds ratio 7.4, 95% confidence interval 1.21-46.24). Procedures on abdomen, emergency surgery, combined anesthesia, and occurrence of intraoperative adverse events were also risk factors for an UIA. Patients with UIA had longer duration of mechanical ventilation than non-UIA patients (4.5 vs. 2 days, p = 0.01), but there were no differences in length of PICU and hospital stays. Preventable adverse events were detected in 25% of UIA children.
Conclusions:
Airway abnormality, anesthetic factors, and hypoxia intraoperative were risk factors associated with UIA. Although preventable events contribute significantly to unplanned PICU admissions, they constitute a room of opportunity in quality improvement programs.
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