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Study of mitral valve in human cadaveric hearts

S A Gunnal1, M S Farooqui, R N Wabale

  • 1Department of Anatomy, Rural Medical College, Maharashtra, India.

Heart Views : the Official Journal of the Gulf Heart Association
|February 27, 2013
PubMed

Insights

The mitral valve, typically considered bicuspid, shows significant morphological variation in cusp number, ranging from one to six. This variability may contribute to valvular disorders.

Area of Science:

  • Anatomy
  • Cardiovascular Research

Background:

  • The mitral valve is a complex cardiac structure.
  • Disease states often alter mitral valve morphology.
  • The classical description is a bicuspid valve with two leaflets.

Purpose of the Study:

  • To investigate the morphology and morphometry of the mitral valve.
  • To document variations in mitral valve cusp number and dimensions.

Main Methods:

  • Analysis of 116 human cadaveric hearts.
  • Measurement of mitral valve annulus diameter and circumference.
  • Observation and classification of mitral valve cusp number.

Main Results:

  • Mean mitral valve annulus diameter was 2.22 cm.
  • Mean mitral valve annulus circumference was 9.12 cm.
  • Mitral valve cusp number varied significantly, from monocuspid to hexacuspid.

Conclusions:

  • The mitral valve is not consistently bicuspid.
  • Significant variation exists in the number of mitral valve cusps.
  • Increased cusp number and improper approximation may lead to valvular disorders.
Abstract

Keywords:
Atrioventricular valveleaflets/cuspsvariation

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