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Anatomical variations of the circulus arteriosus in cadaveric human brains

S A Gunnal1, M S Farooqui1, R N Wabale1

  • 1Department of Anatomy, Rural Medical College, Post Loni Tal Rahata District Ahmednagar, Maharashtra 413736, India.

Neurology Research International
|June 4, 2014
PubMed

Insights

The study found that 40% of Circle of Willis variations occur, with Posterior Cerebral Artery variations being most common. Understanding these anatomical differences is crucial for neurovascular procedures.

Area of Science:

  • Neuroanatomy
  • Vascular Anatomy
  • Cerebrovascular System

Background:

  • The Circle of Willis (CW) is a critical brain vascular structure.
  • It ensures constant blood supply to the brain.
  • Anatomical variations in the CW are frequently observed.

Purpose of the Study:

  • To determine the prevalence of normal and variant Circle of Willis patterns.
  • To analyze the morphological and morphometric characteristics of CW components.
  • To quantify the frequency of different CW variations.

Main Methods:

  • Dissection of 150 formalin-preserved adult human brains.
  • Measurement of dimensions for all CW segments.
  • Documentation and photographic recording of observed variations (aplasia, hypoplasia, duplication, fenestrations).

Main Results:

  • Identified 21 distinct types of Circle of Willis configurations.
  • A normal, complete CW pattern was observed in 60% of specimens.
  • Significant morphological variations were present in 40% of cases, most commonly in the Posterior Communicating Artery (PCoA) and Anterior Communicating Artery (ACoA).

Conclusions:

  • The high incidence of Circle of Willis variations necessitates pre-surgical angiography.
  • Knowledge of these anatomical variations is essential for successful neurovascular interventions.
  • Awareness aids in preventing complications during surgical procedures.

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