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Related Concept Videos

Hand hygiene01:23

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses, temperature changes,...
Accessory Structures of the Skin: Nails01:05

Accessory Structures of the Skin: Nails

Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Nursing Interventions I: Taxonomy of Nursing Interventions01:03

Nursing Interventions I: Taxonomy of Nursing Interventions

Nursing interventions are chosen as part of the planning process to achieve patient outcomes. Once nursing diagnoses are determined, the goals and outcomes are specified, then the nursing interventions are selected and individualized according to the patient's situation.
A nursing intervention is a treatment or action based on scientific concepts and knowledge from the nursing, behavioral, and physical sciences. Identifying and prioritizing nursing interventions based on the desired outcome is...
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...

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Related Experiment Video

Updated: May 13, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Interventions for nail psoriasis.

Anna Christa Q de Vries1, Nathalie A Bogaards, Lotty Hooft

  • 1Department of Dermatology, AcademicMedical Center, Amsterdam, Netherlands.

The Cochrane Database of Systematic Reviews
|February 27, 2013
PubMed
Summary
This summary is machine-generated.

Systemic biologics like infliximab and golimumab, and radiotherapy, showed efficacy in treating nail psoriasis. However, potential serious adverse effects limit their use, necessitating further high-quality research for topical treatments.

Related Experiment Videos

Last Updated: May 13, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Area of Science:

  • Dermatology
  • Rheumatology
  • Evidence-based medicine

Background:

  • Psoriasis commonly affects nails, with incidence increasing with disease duration.
  • Nail psoriasis can be challenging to treat, impacting quality of life.
  • Therapeutic interventions may offer improvement for psoriatic nail conditions.

Purpose of the Study:

  • To systematically evaluate the efficacy and safety of treatments for nail psoriasis.
  • To synthesize evidence from randomized controlled trials (RCTs) on nail psoriasis interventions.

Main Methods:

  • Comprehensive literature search of multiple databases up to March 2012.
  • Inclusion of all RCTs investigating interventions for nail psoriasis.
  • Independent data extraction and risk of bias assessment by two authors.

Main Results:

  • Infliximab and golimumab demonstrated significant nail score improvement compared to placebo.
  • Superficial radiotherapy (SRT) showed significant nail score improvement in one study.
  • Systemic treatments reported mild adverse effects; topical treatments showed inconclusive evidence.

Conclusions:

  • Infliximab, golimumab, and certain radiotherapy types show efficacy for nail psoriasis.
  • Systemic treatments carry risks, making them suitable mainly for severe cases or comorbid conditions.
  • High-quality trials with standardized outcomes are needed, especially for topical therapies.