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Updated: May 13, 2026

Multi-modal Imaging of Angiogenesis in a Nude Rat Model of Breast Cancer Bone Metastasis Using Magnetic Resonance Imaging, Volumetric Computed Tomography and Ultrasound
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[Clinical nuclear medicine in bone metastases]

Joji Kawabe1, Shigeaki Higashiyama, Susumu Shiomi

  • 1Department of Nuclear Medicine, Osaka City University, Japan.

Clinical Calcium
|March 1, 2013
PubMed
Summary

Technetium-99m-hydroxymethylene diphosphonate binds to bone matrix hydroxyapatite, while Strontium-89 incorporates directly into the bone matrix. Accurate uptake assessment in bone metastases is crucial for pain management.

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