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Updated: May 13, 2026

08:49
Models of Bone Metastasis
Published on: September 4, 2012
[Bone metabolic markers for evaluation of bone metastases]
1Department of Medical Oncology, Japanese Foundation for Cancer Research, Japan.
Abstract
None:
Bone metabolic markers consist of bone formation markers, which are secreted from osteoblasts (BAP, OC, P1CP, P1NP) , and bone resorption markers, which are metabolites of bone type 1 collagen or secreted from osteoclasts (PYD, DPD, NTX, CTX, 1CTP, TRACP) . Those bone metabolic markers are useful for : (1) diagnosis of bone metastases, (2) follow-up during treatment of bone metastases, and (3)predicting prognosis of bone metastases.
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