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Published on: July 28, 2018
Self-regulation in a minimal model of chemical self-replication
Sylvia J Lou1, Enrique Peacock-López
1Department of Chemistry, Williams College, Williamstown, MA 01267 USA.
Abstract:
In biological systems, regulation plays an important role in keeping metabolite concentrations within physiological ranges. To study the dynamical implications of self-regulation, we consider a functional form used in genetic networks and couple it to a mechanism associated with chemical self-replication. For the two-variable minimal model, we find that activation can yield chemical toggles similar to those reported for gene repression in E. coli as well as more complex dynamics.
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