Related Experiment Video
Updated: May 13, 2026
08:20
Time-Resolved In Vivo Measurement of Neuropeptide Dynamics by Capacitive Immunoprobe in Porcine Heart
Published on: May 19, 2022
NT-proBNP in Myocarditis after a Scorpion Sting Envenomation
Suresh V Sagarad1, Balaram Singh Thakur, S S Reddy
1Assistant Professor, Department of Medicine, NMC&H, Chief of Cardiology, RGSSH & SHRC , Raichur, India .
Journal of Clinical and Diagnostic Research : JCDR
|March 2, 2013
Summary
Elevated NT-proBNP levels indicate myocarditis following scorpion stings. These N-terminal pro-B-type natriuretic peptide levels were higher than in cardiomyopathy, correlating with cardiac dysfunction.
Area of Science:
- Cardiology
- Toxicology
- Biomarkers
Background:
- Scorpion stings can cause myocarditis, a serious cardiac condition.
- N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a known biomarker for heart strain.
Purpose of the Study:
- To assess NT-proBNP levels in patients with scorpion sting-induced myocarditis.
- To compare these levels with those in heart failure due to cardiomyopathy.
Main Methods:
- Prospective study of 30 scorpion sting patients and 21 cardiomyopathy patients.
- Collected demographic, clinical, echocardiographic data, and NT-proBNP levels.
Main Results:
- 22 patients showed echocardiographic evidence of myocarditis (LVEF < 50%).
- These patients had significantly elevated NT-proBNP levels, especially with severe LV dysfunction.
- NT-proBNP levels were higher in scorpion sting myocarditis than in cardiomyopathy-induced heart failure.
Conclusions:
- NT-proBNP is significantly elevated in myocarditis post-scorpion sting envenomation.
- Elevated NT-proBNP correlates with left ventricular dysfunction and myocarditis severity.
Related Concept Videos
01:19Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
01:27Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
01:14Myocarditis III: Medical Management
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
01:28Diphtheria
Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
01:19Pericarditis II: Clinical Features and Diagnostic Tests
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
01:22Myocarditis IV: Nursing Management
Myocarditis is an inflammatory condition of the myocardium requiring meticulous nursing management for optimal patient outcomes. Effective management begins with a thorough assessment of the patient's medical history, paying close attention to past infections, autoimmune disorders, travel history, and exposure to toxins or drugs. Recent viral infections and systemic diseases are particularly relevant due to their potential role in triggering myocarditis.Physical Examination and MonitoringThe...