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Updated: May 13, 2026
04:11
Endolymphatic Duct Blockage as a Surgical Treatment Option for Ménière's Disease
Published on: April 28, 2023
Surgery for Ménière's disease
Bas Pullens1, Hendrik P Verschuur, Peter Paul van Benthem
1ENT Surgery,University Medical Centre Utrecht, Utrecht, Netherlands.
The Cochrane Database of Systematic Reviews
|March 2, 2013
Summary
Surgical options for Ménière
Area of Science:
- Otolaryngology
- Neurosurgery
- Neurosurgical Procedures
Background:
- Ménière's disease presents with variable vertigo, deafness, and tinnitus.
- Surgical interventions aim to manage Ménière's disease symptoms.
- The efficacy of surgical treatments for Ménière's disease remains unclear.
Purpose of the Study:
- To evaluate the effectiveness of surgical treatments for Ménière's disease.
- To review all surgical interventions for Ménière's disease, including those altering disease progression or abolishing vestibular function.
Main Methods:
- Searched multiple databases (PubMed, EMBASE, CENTRAL, etc.) for relevant trials up to November 2012.
- Included randomized or quasi-randomized controlled studies comparing surgical modalities against placebo.
- Two authors independently assessed trial quality and extracted data.
Main Results:
- Only endolymphatic sac surgery was evaluated in randomized controlled trials meeting inclusion criteria.
- Two trials (59 patients) compared endolymphatic sac surgery with ventilation tubes or simple mastoidectomy.
- No significant beneficial effect of endolymphatic sac surgery was reported compared to placebo or grommet insertion.
Conclusions:
- Current evidence from two randomized trials is insufficient to support the efficacy of endolymphatic sac surgery for Ménière's disease.
- Further high-quality research is needed to determine the effectiveness of surgical interventions for Ménière's disease.
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