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Related Experiment Video

Updated: May 13, 2026

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
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Published on: May 16, 2022

Multiplexed sensing and imaging with colloidal nano- and microparticles.

Susana Carregal-Romero1, Encarnación Caballero-Díaz, Lule Beqa

  • 1Fachbereich Physik and WZMW, Philipps Universität Marburg, Marburg 35043, Germany. susana.carregal@physik.uni-marburg.de

Annual Review of Analytical Chemistry (Palo Alto, Calif.)
|March 5, 2013
PubMed
Summary

Multiplexed sensing and imaging using colloidal nanoparticles have advanced significantly. These techniques enable parallel detection of multiple analytes or labels, enhancing analytical capabilities.

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Last Updated: May 13, 2026

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
07:13

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Published on: May 16, 2022

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Published on: March 13, 2017

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Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy

Published on: July 18, 2014

Area of Science:

  • Nanotechnology
  • Analytical Chemistry
  • Biomedical Imaging

Background:

  • Significant advancements in colloidal nano- and microparticle technology over the past decade.
  • Established applications in sensing and imaging modalities.

Purpose of the Study:

  • To review the concepts and applications of multiplexed sensing and imaging.
  • To highlight the parallel detection capabilities offered by these particle-based techniques.

Main Methods:

  • Review of existing literature on fluorescent, plasmonic, and magnetic colloidal nanoparticles.
  • Analysis of multiplexing strategies for parallel sensing and imaging.

Main Results:

  • Demonstration of parallel sensing of multiple analytes.
  • Illustration of parallel imaging of multiple labels using various nanoparticle types.
  • Discussion of the enhanced analytical throughput enabled by multiplexing.

Conclusions:

  • Multiplexed approaches with colloidal nanoparticles offer powerful parallel detection capabilities.
  • These techniques are crucial for advancing fields requiring simultaneous analysis of multiple targets.