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Updated: May 13, 2026

Isolation and Identification of Mesenchymal Stem Cells Derived from Adipose Tissue of Sprague Dawley Rats
Published on: April 7, 2023
Adipose-derived mesenchymal stem cells and regenerative medicine
Masamitsu Konno1, Atsushi Hamabe, Shinichiro Hasegawa
1Department of Frontier Science for Cancer and Chemotherapy, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Abstract:
Adipose tissue-derived mesenchymal stem cells (ADSCs) are multipotent and can differentiate into various cell types, including osteocytes, adipocytes, neural cells, vascular endothelial cells, cardiomyocytes, pancreatic β-cells, and hepatocytes. Compared with the extraction of other stem cells such as bone marrow-derived mesenchymal stem cells (BMSCs), that of ADSCs requires minimally invasive techniques. In the field of regenerative medicine, the use of autologous cells is preferable to embryonic stem cells or induced pluripotent stem cells. Therefore, ADSCs are a useful resource for drug screening and regenerative medicine. Here we present the methods and mechanisms underlying the induction of multilineage cells from ADSCs.
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