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Published on: July 5, 2021
[Congenital medulloblastoma associated with intracranial arachnoid cyst]
Miguel Gelabert González1, Ramón Serramito-García1, Mercedes Liñares Paz2
1Servicio de Neurocirugía, Departamento de Cirugía, Hospital Clínico Universitario de Santiago, Universidad de Santiago de Compostela, Santiago de Compostela, La Coruña, España.
Insights
This case study highlights a rare association between a pediatric arachnoid cyst and medulloblastoma. Endoscopic treatment for the cyst revealed a previously undetected posterior fossa tumor.
Area of Science:
- Pediatric Neurosurgery
- Neuro-oncology
- Cystic lesions of the central nervous system
Background:
- Arachnoid cysts are common in children, with treatment tailored to location and symptoms.
- These cysts are typically solitary but can co-occur with other CNS pathologies.
Observation:
- A neonate with a quadrigeminal cistern arachnoid cyst underwent endoscopic treatment.
- Post-operatively, the infant's condition deteriorated, revealing a midline posterior fossa tumor on CT scan.
- The tumor, a medulloblastoma, was not apparent on initial preoperative imaging.
Findings:
- The medulloblastoma was partially resected due to the patient's young age and poor prognosis.
- Oncological treatment was withheld given the clinical context.
- This case represents an exceptionally rare co-occurrence of medulloblastoma and arachnoid cyst, with only one prior report in medical literature.
Implications:
- Highlights the importance of thorough post-operative imaging in pediatric neurosurgery.
- Underscores the rare but critical association between arachnoid cysts and CNS tumors.
- Suggests potential diagnostic challenges in identifying co-existing pathologies in neonates.
Abstract:
Arachnoid cysts are very common lesions in paediatric patients, with treatment depending on their location and symptomatology. They are usually solitary cysts but may be associated with other central nervous system diseases such as tumours and congenital deformities. We describe the case of a neonate diagnosed with an arachnoid cyst of the quadrigeminal cistern treated by endoscopy. After the operation, the child's condition worsened; a CT scan revealed a midline posterior fossa tumour not visible in the preoperative neuroradiological tests. The tumour, a medulloblastoma, was partially removed. Given the child's age and the poor prognosis, oncological treatment was not undertaken. The association between medulloblastoma and arachnoid cyst is very rare, and we could find only one such case in the literature.
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