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A 60-year-old lady with leonine facies: a rare diagnosis
Deepti Mutreja1, Abhishek Purohit, Pawan K Singh
1Department of Hematology, All India Institute of Medical Sciences, New Delhi, India.
Abstract:
Systemic mastocytosis is a rare clonal disorder characterized by mast cell infiltration of one or more organs, with or without skin involvement. Leonine facies is a rare presentation and corresponds to the morphologic manifestation of diffuse dermal infiltration of the face as a result of long standing disease. Bone marrow aspiration and biopsy findings in a 60-year-old woman, who had extensive cutaneous infiltration due to systemic mastocytosis, resulting in 'leonine facies,' are described, and causes of leonine facies are discussed.
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