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Related Experiment Video

Updated: May 13, 2026

Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI
10:50

Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI

Published on: February 19, 2014

Sudden behavior change in a cat.

H B Gelberg1

  • 1Department of Biomedical Sciences and the Veterinary Diagnostic Laboratory, College of Veterinary Medicine, 233 Magruder Hall, Oregon State University, Corvallis, OR 97331, USA.

Veterinary Pathology
|March 5, 2013
PubMed
Summary
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A cat experienced sudden behavioral changes and seizures. Neuropathological examination revealed hippocampal damage, suggesting a neurological disorder rather than a detectable brain mass.

Area of Science:

  • Veterinary Neurology
  • Comparative Pathology

Background:

  • Sudden behavioral changes and seizures in cats can indicate serious underlying neurological conditions.
  • Diagnostic challenges exist in identifying the etiology of acute neurological signs in felines.

Observation:

  • A 5-year-old domestic short-haired cat presented with a 10-day history of acute behavioral changes and seizures.
  • Routine blood work and radiographs were unremarkable, ruling out common systemic or structural brain abnormalities.
  • Rabies testing was negative, and no gross lesions were observed post-mortem.

Findings:

  • Histological examination of the brain revealed focal hippocampal pyramidal cell loss.
  • Evidence of mild gliosis, neuropil pallor, and neovascularization was noted within the affected brain regions.
Keywords:
encephalopathyfelinehippocampus

Related Experiment Videos

Last Updated: May 13, 2026

Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI
10:50

Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI

Published on: February 19, 2014

  • These microscopic changes indicate neuronal injury and a reactive inflammatory or reparative process in the feline brain.

    • Implications:

    • The observed neuropathological findings suggest a specific type of acute neuronal injury or encephalitis in the cat.
    • This case highlights the importance of detailed histopathology for diagnosing neurological diseases in cats presenting with non-specific signs.
    • Further research may elucidate the etiology of such hippocampal lesions in domestic felines.