Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The experience of cognitive conflict is intrinsically rewarding.

Communications psychology·2026
Same author

Clinical utility and prospective of TMS-EEG: Updated review from an international expert group.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
Same author

Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines (2017-2025: An update) - endorsed by the European Society for Brain Stimulation (ESBS) and by the International Federation for Clinical Neurophysiology (IFCN).

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
Same author

Negative Affective Traits Moderate Transcranial Direct Current Stimulation Effects on Memory.

Biological psychiatry. Cognitive neuroscience and neuroimaging·2025
Same author

Stimulation of the right dorsolateral prefrontal cortex reduces conflict-induced forgetting.

Cerebral cortex (New York, N.Y. : 1991)·2025
Same author

Harnessing neural variability: Implications for brain research and non-invasive brain stimulation.

Neuroscience and biobehavioral reviews·2025

Related Experiment Video

Updated: May 13, 2026

Simultaneous Transcranial Alternating Current Stimulation and Functional Magnetic Resonance Imaging
10:25

Simultaneous Transcranial Alternating Current Stimulation and Functional Magnetic Resonance Imaging

Published on: June 5, 2017

Is transcranial alternating current stimulation effective in modulating brain oscillations?

Debora Brignani1, Manuela Ruzzoli, Piercarlo Mauri

  • 1Cognitive Neuroscience Section, IRCCS Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy. debora.brignani@cognitiveneuroscience.it

Plos One
|March 5, 2013
PubMed
Summary

Transcranial alternating current stimulation (tACS) showed mixed results in modulating brain oscillations. This study found no significant evidence that tACS reliably influences visual task performance, limiting its therapeutic potential.

More Related Videos

Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats
10:51

Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats

Published on: May 11, 2018

Effects of Transcranial Alternating Current Stimulation on the Primary Motor Cortex by Online Combined Approach with Transcranial Magnetic Stimulation
11:11

Effects of Transcranial Alternating Current Stimulation on the Primary Motor Cortex by Online Combined Approach with Transcranial Magnetic Stimulation

Published on: September 23, 2017

Related Experiment Videos

Last Updated: May 13, 2026

Simultaneous Transcranial Alternating Current Stimulation and Functional Magnetic Resonance Imaging
10:25

Simultaneous Transcranial Alternating Current Stimulation and Functional Magnetic Resonance Imaging

Published on: June 5, 2017

Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats
10:51

Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats

Published on: May 11, 2018

Effects of Transcranial Alternating Current Stimulation on the Primary Motor Cortex by Online Combined Approach with Transcranial Magnetic Stimulation
11:11

Effects of Transcranial Alternating Current Stimulation on the Primary Motor Cortex by Online Combined Approach with Transcranial Magnetic Stimulation

Published on: September 23, 2017

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Neurostimulation

Background:

  • Transcranial alternating current stimulation (tACS) is explored for modulating brain oscillations and therapeutic applications.
  • Conclusive evidence on tACS's efficacy in affecting cortical activity remains limited.
  • The alpha rhythm in the posterior parietal cortex is a key target for visual perception and attention studies.

Purpose of the Study:

  • To investigate the effectiveness of tACS in modulating brain oscillations and influencing visual task performance.
  • To assess the impact of specific tACS frequencies (6 Hz, 10 Hz, 25 Hz) on visual detection and discrimination.
  • To determine if tACS reliably affects cortical activity relevant to visual perception.

Main Methods:

  • Healthy volunteers participated in a visual Gabor patch detection and discrimination task.
  • Participants received tACS at baseline, sham, 6 Hz, 10 Hz, and 25 Hz over the occipito-parietal area.
  • Performance metrics were analyzed to evaluate the effects of different tACS frequencies.

Main Results:

  • tACS at 6 Hz and 10 Hz impaired performance in the detection task compared to baseline.
  • No significant retinotopically organized effect was observed.
  • Modulation of performance showed only marginal frequency specificity.

Conclusions:

  • The study did not find significant evidence for tACS reliably inducing direct modulations of brain oscillations.
  • Observed effects on visual task performance were not consistently frequency-specific or retinotopically organized.
  • Further research is needed to establish the efficacy and mechanisms of tACS in modulating cognitive functions.