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Updated: May 13, 2026

Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice
08:21

Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice

Published on: June 15, 2020

[Treatment of valvular heart diseases with catheterization techniques]

Mika Laine1, Markku Eskola, Janne Rapola

  • 1Helsingin yliopistollinen sairaala, kardiologian klinikka.

Duodecim; Laaketieteellinen Aikakauskirja
|March 6, 2013
PubMed

Insights

Transcatheter therapies offer alternatives for valvular heart disease when open heart surgery is too risky. These minimally invasive catheter-based treatments include aortic valve replacement and mitral valve repair, benefiting older patients.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Medical Technology

Context:

  • Valvular heart disease (VHD) incidence rises with age.
  • Open-heart surgery poses significant risks for elderly patients and those with comorbidities.
  • Traditional surgical interventions may not be suitable for all VHD patients.

Purpose:

  • To review current catheter-based therapies for valvular heart disease.
  • To discuss the clinical applications of transcatheter aortic valve implantation (TAVI).
  • To explore transcatheter mitral valve repair (TMVR) using clip implantation.

Summary:

  • This review covers two minimally invasive catheter therapies for VHD: TAVI and TMVR.
  • Transcatheter aortic valve implantation involves inserting an artificial aortic valve via catheter.
  • Transcatheter mitral valve repair utilizes clip implantation through transvenous access.

Impact:

  • Provides less invasive treatment options for high-risk VHD patients.
  • Expands treatment accessibility for valvular heart conditions in the elderly.
  • Highlights advancements in interventional cardiology for managing VHD.

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