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Published on: November 9, 2016
Extraction and characterization of mango peel pectin as pharmaceutical excipient
Rishabha Malviya1, Giraj T Kulkarni
1Rexcin Pharmaceuticals Private Limited, Vill. Katha Baddi, Plot No-105-106, Baddi, Distt-Solon, Himachal Pradesh, India rishabhamalviya19@gmail.com
Aim Of Study:
Present study includes extraction and characterization the mango peel derived pectin as a pharmaceutical excipients.
Material And Methods:
Pectin was obtained using acidified water based extraction in soxhlet apparatus. To characterize the extracted pectin phytochemical screening was done and micromeritic properties, flow behavior, surface tension, viscosity and swelling index were calculated.
Results:
Using water based extraction method 25.26% yield of pectin was obtained. The result revealed the fact that extracted mango peel pectin exhibited good flow properties (angle of repose 28.01), 41.90 +/- 2.62 dynes/cm2 surface tension, 0.46% w/w total ash, 0.76% loss on drying and pH was found 4.15, showed that this can be used in dosage form, without any irritation. Extracted pectin was soluble in warm water while insoluble in organic solvents.
Conclusions:
Results of evaluated parameters showed that mango peel derived pectin can be used as pharmaceutical excipient to prepare solid oral dosage form.
