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Related Concept Videos

Investigation of Disease Outbreaks01:23

Investigation of Disease Outbreaks

Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
Patterns of Fever01:26

Patterns of Fever

Before understanding the types and patterns of fever, it is essential to know its phases.
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
Cholera01:25

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...

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Related Experiment Video

Updated: May 13, 2026

Protocol for Dengue Infections in Mosquitoes (A. aegypti) and Infection Phenotype Determination
15:25

Protocol for Dengue Infections in Mosquitoes (A. aegypti) and Infection Phenotype Determination

Published on: July 4, 2007

Dengue fever outbreak in Lahore.

Usman Hassan1, Asif Loya, Muhammad Tariq Mehmood

  • 1Department of Pathology, Shaukat Khanum Memorial Cancer Hospital, Lahore. usman_hassan256@hotmail.com

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|March 6, 2013
PubMed
Summary

Antibody screening identified dengue fever in 3.1% of patients tested in Lahore during a 2010 epidemic. This highlights the significant impact of dengue fever in the region, necessitating increased awareness.

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Visualizing Dengue Virus through Alexa Fluor Labeling
09:11

Visualizing Dengue Virus through Alexa Fluor Labeling

Published on: July 9, 2011

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Last Updated: May 13, 2026

Protocol for Dengue Infections in Mosquitoes (A. aegypti) and Infection Phenotype Determination
15:25

Protocol for Dengue Infections in Mosquitoes (A. aegypti) and Infection Phenotype Determination

Published on: July 4, 2007

Visualizing Dengue Virus through Alexa Fluor Labeling
09:11

Visualizing Dengue Virus through Alexa Fluor Labeling

Published on: July 9, 2011

Area of Science:

  • Infectious Diseases
  • Epidemiology
  • Immunology

Background:

  • Dengue fever is a growing global health concern.
  • Major cities in the country, including Lahore, have been significantly affected by dengue outbreaks.
  • The 2010 floods exacerbated the dengue situation in Lahore.

Purpose of the Study:

  • To determine the seroprevalence of dengue fever in Lahore during the 2010 epidemic.
  • To assess the frequency of IgM and IgG antibodies in patients presenting with dengue-like symptoms.

Main Methods:

  • Antibody screening for dengue fever was conducted.
  • A total of 41,354 patients were tested at Shaukat Khanum Memorial Cancer Hospital, Lahore.
  • Testing occurred during the epidemic period from October 1st to December 20th, 2010.

Main Results:

  • Out of 41,354 patients, 1294 (3.1%) tested positive for IgM antibodies.
  • 124 (0.3%) patients were positive for IgG antibodies.
  • Borderline positive results were observed in 722 (1.7%) for IgM and 108 (0.26%) for IgG antibodies.

Conclusions:

  • Dengue fever posed a significant public health challenge in Lahore in 2010.
  • The study underscores the importance of diagnostic screening for dengue during outbreaks.
  • A high index of suspicion for dengue is recommended for patients with related symptoms.