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Related Experiment Video

Updated: May 13, 2026

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section
11:00

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section

Published on: July 19, 2016

Hydrodynamic flow through loading and in vitro secondary caries development.

N K Kuper1, N J M Opdam, E M Bronkhorst

  • 1College of Dental Sciences, Department of Preventive and Restorative Dentistry, Radboud University Nijmegen Medical Centre, P.O. Box 9101, NL 6500 HB Nijmegen, The Netherlands. n.kuper@dent.umcn.nl

Journal of Dental Research
|March 6, 2013
PubMed
Summary
This summary is machine-generated.

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Mechanical loading and lack of bonding significantly increase secondary caries lesion development in bovine teeth. Higher loads and unbonded interfaces resulted in more advanced enamel and dentin lesions.

Area of Science:

  • Dental Materials Science
  • Caries Research
  • Biomaterials Engineering

Background:

  • Secondary caries remains a significant challenge in restorative dentistry.
  • Understanding factors influencing secondary caries at the restoration-tooth interface is crucial.

Purpose of the Study:

  • To investigate the impact of hydrodynamic flow induced by mechanical loading on secondary caries development.
  • To evaluate the role of bonding in mitigating mechanical loading effects on lesion progression.

Main Methods:

  • In vitro study using 48 bovine tooth specimens with resin-composite restorations.
  • Artificial secondary caries lesions were induced using lactic acid under mechanical loading.
  • Transverse wavelength-independent microradiography (T-WIM) assessed lesion depth and mineral loss.

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Published on: November 3, 2015

Related Experiment Videos

Last Updated: May 13, 2026

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section
11:00

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section

Published on: July 19, 2016

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling
07:30

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling

Published on: November 3, 2015

Main Results:

  • Higher mechanical loading (350 gr) significantly increased lesion depth and mineral loss compared to lower loads (200 gr).
  • Absence of bonding (non-bonded) led to significantly more advanced lesions than bonded interfaces under the same loading conditions.
  • Mechanical loading induced opening forces at the tooth-composite interface, exacerbating lesion development.

Conclusions:

  • Hydrodynamic flow through mechanical loading promotes secondary caries progression.
  • Bonding of resin-composite restorations is critical in preventing mechanical loading-induced secondary caries.
  • Clinical implications include optimizing bonding protocols and considering mechanical forces in restoration design.