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Related Experiment Video

Updated: May 13, 2026

Visualizing Diffusional Dynamics of Gold Nanorods on Cell Membrane using Single Nanoparticle Darkfield Microscopy
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Visualizing Diffusional Dynamics of Gold Nanorods on Cell Membrane using Single Nanoparticle Darkfield Microscopy

Published on: March 5, 2021

Visualizing nanoparticle mobility in liquid at atomic resolution.

Madeline J Dukes1, Benjamin W Jacobs, David G Morgan

  • 1Applications Science, Protochips, Inc., Raleigh, NC, USA.

Chemical Communications (Cambridge, England)
|March 6, 2013
PubMed
Summary
This summary is machine-generated.

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Gold nanorods show potential for high-resolution imaging in liquid using Transmission Electron Microscopy (TEM). This study presents the first atomic measurements of functionalized nanorods in solution, visualizing their dynamic behavior.

Area of Science:

  • Nanotechnology
  • Materials Science
  • Biomedical Imaging

Background:

  • Gold nanorods are recognized for their photothermal capabilities in solid tumor treatment.
  • Current imaging techniques often lack the resolution to observe nanorods in their native liquid environment.
  • Understanding nanorod behavior in solution is crucial for optimizing their therapeutic applications.

Purpose of the Study:

  • To demonstrate the high-resolution imaging capacity of gold nanorods in liquid using Transmission Electron Microscopy (TEM).
  • To perform the first atomic-level measurements of functionalized gold nanorods in solution.
  • To visualize the dynamic behavior of gold nanorods in a liquid environment.

Main Methods:

  • Utilizing Transmission Electron Microscopy (TEM) for high-resolution imaging.

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Revealing Dynamic Processes of Materials in Liquids Using Liquid Cell Transmission Electron Microscopy
07:37

Revealing Dynamic Processes of Materials in Liquids Using Liquid Cell Transmission Electron Microscopy

Published on: December 20, 2012

Related Experiment Videos

Last Updated: May 13, 2026

Visualizing Diffusional Dynamics of Gold Nanorods on Cell Membrane using Single Nanoparticle Darkfield Microscopy
09:09

Visualizing Diffusional Dynamics of Gold Nanorods on Cell Membrane using Single Nanoparticle Darkfield Microscopy

Published on: March 5, 2021

Liquid-cell Transmission Electron Microscopy for Tracking Self-assembly of Nanoparticles
08:39

Liquid-cell Transmission Electron Microscopy for Tracking Self-assembly of Nanoparticles

Published on: October 16, 2017

Revealing Dynamic Processes of Materials in Liquids Using Liquid Cell Transmission Electron Microscopy
07:37

Revealing Dynamic Processes of Materials in Liquids Using Liquid Cell Transmission Electron Microscopy

Published on: December 20, 2012

  • Functionalizing gold nanorods for enhanced measurement capabilities.
  • Conducting atomic measurements of nanorods in aqueous solution.

    • Main Results:

    • Achieved high-resolution imaging of gold nanorods in liquid.
    • Successfully performed atomic measurements of functionalized nanorods.
    • Visualized the dynamic behavior of nanorods in solution using TEM.

    Conclusions:

    • Transmission Electron Microscopy (TEM) offers significant potential for imaging gold nanorods in liquid at high resolution.
    • This work provides foundational atomic-level data on nanorods in solution.
    • The findings pave the way for improved understanding and application of gold nanorods in biomedical fields, particularly in cancer therapy.