Related Experiment Video
Updated: Jan 11, 2026

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment
Published on: November 17, 2018
Office-related antibiotic prescribing for Medicaid-enrolled children
Randall J Nett1, David Campana, Cody L Custis
1Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA. ggE5@cdc.gov
Insights
Antibiotic prescribing for acute respiratory infections (ARIs) in children did not change between 1999 and 2010. This highlights a need for improved antibiotic stewardship to combat resistance.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Prudent antibiotic prescribing is crucial for limiting antibiotic resistance.
- Antibiotic overuse for acute respiratory infections (ARIs) contributes to resistance.
Purpose of the Study:
- To evaluate trends in antibiotic prescription rates for pediatric ARIs.
- To assess changes in office visits for ARIs linked to antibiotic prescriptions from 1999 to 2010.
Main Methods:
- Retrospective analysis of Montana Medicaid claims data (1999-2010).
- Included continuously enrolled children aged 14 years or younger.
- Examined ARI-related office visits and antibiotic prescriptions within 10 days.
Main Results:
- 13% of 873,244 office visits were for ARIs.
- 55% of ARI visits (64,250) were linked to antibiotic prescriptions.
- No significant change in the odds of ARI visits receiving antibiotics observed (OR=1.00).
Conclusions:
- The rate of antibiotic prescriptions for pediatric ARIs remained stable from 1999 to 2010.
- Current prescribing practices require further efforts to reduce unnecessary antibiotic use for ARIs.
- Addressing antibiotic resistance necessitates improved stewardship for common infections.
Background:
Prudent antibiotic prescribing practices are essential to limiting antibiotic resistance.
Objective:
To assess the trend in percentage of office visits for acute respiratory infections (ARIs) linked with an antibiotic prescription.
Methods:
Retrospective analysis of Montana Medicaid billing claims data for each year, 1999 to 2010, was done. Participants included continuously enrolled children aged ≤14 years. Primary outcomes were ARI-related office visits and filled antibiotic prescriptions within 10 days of the office visit.
Results:
Of the 873 244 office visits identified, 116 962 (13%) had an ARI as the primary diagnosis. Among ARI-related office visits, 64 250 (55%) were linked with an antibiotic prescription. From 1999 to 2010, the odds of ARI-related visits being linked with an antibiotic prescription did not change (odds ratio = 1.00; 95% confidence interval = 0.995-1.002).
Conclusions:
The percentage of ARI-related visits linked with an antibiotic prescription did not decrease from 1999 to 2010. Further efforts are needed to reduce antibiotic treatment for ARIs.
Related Concept Videos
Drug Dosing: Infants and Children
Pharmacokinetics in Pediatric Patients: Drug Excretion
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Prescription, Nonprescription and Orphan Drugs
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Antibiotic Selection
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

