Related Experiment Video
Updated: May 13, 2026
06:31
Murine Bilateral Renal Lymphadenectomy
Published on: December 30, 2025
Paraneoplastic subacute cutaneous lupus erythematosus: an underrecognized entity
Katherine G Evans1, Warren R Heymann
1Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, USA.
Cutis
|March 7, 2013
Summary
Subacute cutaneous lupus erythematosus (SCLE) can signal hidden cancer. Early cancer screening is vital when SCLE appears without a known cause.
Area of Science:
- Dermatology
- Oncology
Background:
- Subacute cutaneous lupus erythematosus (SCLE) is typically idiopathic or drug-induced.
- Few cases link SCLE to malignancy, suggesting a potential paraneoplastic subset.
Observation:
- A patient presented with SCLE.
- The SCLE developed concurrently with small cell lung cancer.
Findings:
- This case suggests SCLE can be a paraneoplastic phenomenon.
- SCLE's appearance alongside small cell lung cancer supports this link.
Implications:
- New-onset SCLE warrants thorough medical review and cancer screening.
- SCLE may indicate an underlying, undiagnosed malignancy.
