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Updated: May 13, 2026

Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model
Published on: August 5, 2021
Retinal degenerative diseases--mechanisms and perspectives of treatment
Robert Rejdak1, Małgorzata Szkaradek, Maciej Czepita
1Department of General Ophthalmology, Medical University of Lublin, Lublin, Poland. robertrejdak@yahoo.com
Abstract:
Retinal degenerative diseases are an extensive group of ocular diseases, leading to vision disorders and finally irreversible vision loss. They are an significant problem, because degenerative processes exist in common ocular disorders like glaucoma or age-related macular degeneration and many other less frequently occurring disorders. In this article, we present mechanisms leading to retinal degeneration like excitotoxicity, oxidative stress, inflammation and summarize the latest reports concerning neuroprotection in the treatment of retina degenerative diseases.
