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Updated: May 13, 2026

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High-throughput, Microscale Protocol for the Analysis of Processing Parameters and Nutritional Qualities in Maize (Zea mays L.)
Published on: June 16, 2018
Entering the second century of maize quantitative genetics
J G Wallace1, S J Larsson, E S Buckler
1Institute for Genomic Diversity, Cornell University, Ithaca, NY, USA.
Heredity
|March 7, 2013
Summary
Maize genetics research reveals complex traits are controlled by many genes with rare alleles. These findings offer insights into outcrossing species, including humans.
Area of Science:
- Plant genetics
- Agricultural science
- Genomics
Background:
- Maize is a globally significant crop and a vital model organism for genetic research.
- Its genetic architecture resembles outcrossing species, offering unique insights compared to self-pollinating plants.
- Recent advancements provide powerful tools for dissecting complex maize traits.
Purpose of the Study:
- To review recent progress in maize genetics.
- To explore genetic mechanisms underlying complex maize traits.
- To highlight maize's utility in studying outcrossing species.
Main Methods:
- Utilizing advanced genetic mapping populations.
- Employing genome-wide association studies (GWAS).
- Analyzing linkage and genetic variation models.
Main Results:
- Most maize traits are polygenic, influenced by numerous genes with rare alleles.
- Natural alleles typically have small effect sizes, with limited pleiotropy or epistasis.
- Low-recombination regions harbor multi-gene blocks potentially driving heterosis.
Conclusions:
- Maize's genetic makeup provides a valuable model for understanding outcrossing species.
- Domestication has significantly shaped the maize genome and trait architecture.
- Insights from maize genetics can inform studies in other outcrossing organisms, including humans.
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