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Published on: May 9, 2014
'Marker-of-self' functionalization of nanoscale particles through a top-down cellular membrane coating approach
Che-Ming J Hu1, Ronnie H Fang, Brian T Luk
1Department of NanoEngineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Nanoscale
|March 7, 2013
Abstract:
We investigate the 'marker-of-self' functionalization of nanoparticles through coating of natural RBC membranes. The membrane translocation approach is shown to be highly efficient and bestows nanoparticles with correctly oriented and functional immunomodulatory proteins such as CD47 at equivalent density to natural RBCs.
