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Related Concept Videos

lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...
Types of RNA01:20

Types of RNA

Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in regulating gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA Performs Diverse...
Types of RNA01:23

Types of RNA

Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
Types of RNA01:23

Types of RNA

Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
Types of RNA01:20

Types of RNA

Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in regulating gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA Performs Diverse...

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Related Experiment Video

Updated: May 13, 2026

RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA
09:36

RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA

Published on: April 10, 2018

Long noncoding RNAs: past, present, and future.

Johnny T Y Kung1, David Colognori, Jeannie T Lee

  • 1Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02114, USA.

Genetics
|March 7, 2013
PubMed
Summary

Long noncoding RNAs (lncRNAs) are key regulators in biology and disease, but their functions and mechanisms remain under investigation. This review explores lncRNA roles, genomic contexts, and evolutionary significance.

Area of Science:

  • Molecular Biology
  • Genomics
  • Epigenetics

Background:

  • Long noncoding RNAs (lncRNAs) represent a significant regulatory layer in biological systems.
  • Their roles in development and disease are increasingly recognized, yet mechanistic understanding is limited.
  • The extent of functional noncoding transcription across the mammalian genome is still debated.

Purpose of the Study:

  • To review the current understanding of lncRNA biology.
  • To discuss known genomic contexts, biological functions, and mechanisms of action for lncRNAs.
  • To contextualize recent lncRNA research within the broader study of genome evolution and function.

Main Methods:

  • Literature review of current lncRNA research.
  • Synthesis of findings on lncRNA genomic organization.

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Chromatin Isolation by RNA Purification (ChIRP)
11:09

Chromatin Isolation by RNA Purification (ChIRP)

Published on: March 25, 2012

Related Experiment Videos

Last Updated: May 13, 2026

RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA
09:36

RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA

Published on: April 10, 2018

Chromatin Isolation by RNA Purification (ChIRP)
11:09

Chromatin Isolation by RNA Purification (ChIRP)

Published on: March 25, 2012

  • Analysis of documented lncRNA functions and regulatory mechanisms.

    • Main Results:

    • A growing number of lncRNAs are linked to diverse biological processes and diseases.
    • Emerging themes in lncRNA function and mechanism provide initial insights.
    • Robust models and classification systems for lncRNAs are still developing.

    Conclusions:

    • lncRNAs are critical regulatory molecules with diverse roles.
    • Further research is needed to fully elucidate lncRNA mechanisms and functions.
    • The study of lncRNAs connects to fundamental questions in genome evolution and function.