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Related Experiment Video

Updated: May 13, 2026

A Protocol for Roux-en-Y Gastric Bypass in Rats using Linear Staplers

A Protocol for Roux-en-Y Gastric Bypass in Rats using Linear Staplers

Published on: August 21, 2021

Risk management protocol for gastrostomy and jejunostomy insertion in ventilator dependent infants.

M Chatwin¹, A Bush, D J Macrae

¹Clinical and Academic Department of Sleep and Breathing, Royal Brompton & Harefield NHS Foundation Trust, United Kingdom. m.chatwin@rbht.nhs.uk

Neuromuscular Disorders : NMD

|March 8, 2013

Summary

Surgical interventions like gastrostomy and anti-reflux procedures in ventilator-dependent children are risky. However, careful pre-operative assessment and management in this high-risk cohort led to successful outcomes with early extubation and minimal complications.

Related Experiment Videos

Last Updated: May 13, 2026

A Protocol for Roux-en-Y Gastric Bypass in Rats using Linear Staplers

A Protocol for Roux-en-Y Gastric Bypass in Rats using Linear Staplers

Published on: August 21, 2021

Area of Science:

Pediatric Surgery
Critical Care Medicine
Gastroenterology

Background:

Gastrostomy, gastrojejunostomy, and anti-reflux surgery carry significant risks in chronically ventilator-dependent infants and children.
These procedures are often necessary for nutritional support and managing complications in this vulnerable population.

Purpose of the Study:

To evaluate the outcomes of high-risk, ventilator-dependent children undergoing gastrostomy, gastrojejunostomy, and anti-reflux surgery.
To assess the safety and efficacy of a specific pre-operative and post-operative management protocol.

Main Methods:

A cohort of 22 high-risk children requiring ventilatory support underwent 24 surgical procedures.
Pre-operative evaluation included cardiorespiratory monitoring, echocardiography, video fluoroscopy, and reflux assessment.
Procedures were performed under general anesthesia, followed by early extubation and aggressive airway clearance.

Main Results:

No post-operative mortality was observed.
87% of children were successfully extubated within 24 hours.
Minor complications included atelectasis, ileus, abdominal distension, and loose stools.

Conclusions:

Careful pre-operative assessment and optimized ventilatory support enable safe surgical interventions in ventilator-dependent children.
Early extubation and aggressive airway management are feasible and associated with good outcomes.
This approach minimizes post-operative complications in high-risk pediatric surgical patients.