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Updated: May 13, 2026

Orthotopic Hind Limb Transplantation in the Mouse
Published on: February 12, 2016
Cross-over limb replantation: a case report
W J M Holmes1, A Williams, K J M Everitt
1Department of Hand and Plastic Surgery, Leeds General Infirmary, Great George Street, Leeds LS1 0UX, United Kingdom. willjmholmes@googlemail.com
Abstract:
Following traumatic bilateral arm amputation in a 46-year-old woman, orthotopic replantation was not possible. The patient underwent replantation of the left forearm to the right proximal forearm. At two years she has a sensate hand, with good recovery of her long flexors of the hand and wrist extensors. DASH score is 93.9 and Chen's score is III (medium). We demonstrate a high level of function compared to the contralateral prosthetic limb. There have only been four similar cases described. Although a rare circumstance, a cross-limb replant can provide a level of function and independence superior to a simple prosthesis. Cross-limb transfer should be considered in situations where bilateral arm amputation is present and neither can be orthotopically replanted.
