Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

MALDI-TOF Mass Spectrometry

MALDI-TOF Mass Spectrometry

Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...

Mass Spectrometry: Complex Analysis

Mass Spectrometry: Complex Analysis

Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The MassBank contributions of the mFam collaboration.

Metabolomics : Official journal of the Metabolomic Society·2026

Same author

LIPID MAPS: Powering discovery in lipidomics.

Science signaling·2026

Same author

Development of a multi-targeted metabolomics platform for semi-quantification of faecal metabolites: a proof-of-concept analysis in human faeces.

Microbiome research reports·2026

Same author

SMASH Imaging: A Serial Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Strategy for High-Resolution Imaging Facilitates Dual-Polarity and MS2 Spatial Lipidomics on a Single Tissue Section.

Analytical chemistry·2026

Same author

Prediction of the current state of beer fermentation indicators using volatile organic compounds from fermentation gas.

Journal of bioscience and bioengineering·2026

Same author

Metabolomics-based investigation of compounds associated with sensory profiles of strawberries.

Journal of bioscience and bioengineering·2026

Search research articles

Related Experiment Video

Updated: May 13, 2026

A Strategy for Sensitive, Large Scale Quantitative Metabolomics

A Strategy for Sensitive, Large Scale Quantitative Metabolomics

Published on: May 27, 2014

Current metabolomics: technological advances.

Sastia P Putri¹, Shinya Yamamoto, Hiroshi Tsugawa

¹Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.

Journal of Bioscience and Bioengineering

|March 8, 2013

Summary

This summary is machine-generated.

Metabolomics offers a snapshot of cell physiology by quantifying metabolites. This review covers the latest analytical techniques and data analysis methods for metabolomics studies.

More Related Videos

Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS)

Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS)

Published on: March 14, 2013

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

Published on: November 29, 2024

Related Experiment Videos

Last Updated: May 13, 2026

A Strategy for Sensitive, Large Scale Quantitative Metabolomics

A Strategy for Sensitive, Large Scale Quantitative Metabolomics

Published on: May 27, 2014

Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS)

Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS)

Published on: March 14, 2013

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

Published on: November 29, 2024

Area of Science:

Biochemistry
Systems Biology
Genomics

Background:

Metabolomics provides a global assessment of metabolites, reflecting genome-environment interactions.
Metabolites are integral to cellular regulation, not just end products of gene expression.
Metabolomics offers an instantaneous view of cellular physiology.

Purpose of the Study:

To review recent advancements in analytical techniques for metabolomics.
To discuss emerging data analysis methods in metabolomics.

Main Methods:

Quantitative assessment of metabolites in biological systems.
Application of various data analysis tools for extracting meaningful information.
Review of current literature on metabolomics techniques and analysis.

Main Results:

Highlighting the pivotal role of metabolomics in the post-genomic era.
Demonstrating the utility of metabolomics in understanding cellular physiology.
Identifying key developments in analytical and data processing methodologies.

Conclusions:

Metabolomics is a powerful tool for understanding biological systems.
Advancements in analytical techniques and data analysis enhance metabolomics capabilities.
Continued development is crucial for the future of metabolomics research.