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Primary angiosarcoma of breast: A case report.
Suresh Jaywantrao Bhosale1, Ashok Yadavrao Kshirsagar, Mandar Vilas Patil
1Department of Surgery, Krishna Institute of Medical Sciences, Karad 415 110, Maharashtra, India.
International Journal of Surgery Case Reports
|March 8, 2013
Summary
Primary breast angiosarcoma is a rare cancer. Complete surgical removal is the main treatment, offering the best prognosis for this aggressive malignancy.
Area of Science:
- Oncology
- Surgical Pathology
Background:
- Primary breast angiosarcoma is an exceptionally rare malignancy, representing only 0.04% of all breast cancers.
- This rare breast cancer typically affects women in their third to fourth decades of life.
Purpose of the Study:
- To present a case of primary breast angiosarcoma.
- To discuss the diagnostic and treatment modalities for this rare breast malignancy.
Main Methods:
- A case report of a 28-year-old woman with a progressive right breast lump.
- Diagnosis confirmed via fine needle aspiration cytology (FNAC) and core needle biopsy.
- Treatment involved modified radical mastectomy.
Main Results:
- Histological grading (I, II, III) impacts prognosis, with 5-year disease-free survival rates of 76% for grade I, 70% for grade II, and 15% for grade III.
- Complete resection via mastectomy is the primary treatment modality.
Conclusions:
- Primary breast angiosarcoma is a rare and aggressive cancer with a poor prognosis, even after complete resection.
- Surgery is the cornerstone of treatment; chemotherapy and radiotherapy have limited proven efficacy.
- Mastectomy offers the most benefit for patients diagnosed with breast angiosarcoma.
