[The effect of low concentrations of urea on immunoglobulin conformation from the data of differential

Biofizika
|January 1, 1990
PubMed

A reversible noncooperative conformational transition takes place in IgG molecule at 1 divided by 3 M urea solutions in the temperature interval 10 divided by 40 degrees C. This transition is registered as an increase of chromophores exposure and preceeds denaturation which happens at the same temperatures and with higher urea concentration.

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