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Birth defects after incestuous mating: calculating the probability of causality and reflecting on the desirability of
Leo P Ten Kate1, Matthias Rath, Ute Felbor
1Department of Clinical Genetics and Institute of Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands. lp.tenkate@vumc.nl
Abstract:
In this short communication we (1) show that, despite the rarity of autosomal recessive inheritance, primary congenital hydrocephalus in a girl stemming from father-daughter incest is most likely due to the incestuous union of her parents, and (2) reflect on the question, among others, whether actual genetic work-up to support victim indemnification is ever in the interest of the child.
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